The neurological impact of post-traumatic stress disorder on the development of degenerative diseases
DOI:
https://doi.org/10.56294/shp2024113Keywords:
post-traumatic stress disorder, dementia, neurodegeneration, chronic stress, neuroinflammationAbstract
Post-traumatic stress disorder (PTSD) from a neurobiological perspective, beyond its traditional psychological approach. The study analysed how PTSD, by inducing alterations in brain areas such as the hippocampus and prefrontal cortex, may have increased the risk of developing frontotemporal dementia (FTD). The research reviewed identified common mechanisms between the two conditions, such as neuroinflammation and synaptic dysfunction, which suggested a possible causal link. Furthermore, it was considered that chronic stress may not only have acted as a trigger for neurodegenerative diseases, but may also have been aggravated by them. Finally, it was proposed that early identification and management of chronic stress could have contributed to preventing or delaying the onset of FTD.
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Copyright (c) 2024 Fabiane Simone Deprá , Liliana Lombisani (Author)
This work is licensed under a Creative Commons Attribution 4.0 International License.
The article is distributed under the Creative Commons Attribution 4.0 License. Unless otherwise stated, associated published material is distributed under the same licence.
