Clinical epidemiological characterization of laryngeal cancer, hospital: Abel Santamaría Cuadrado
DOI:
https://doi.org/10.56294/shp202380Keywords:
clinical epidemiological, cancer, laryngeal cancerAbstract
An observational, descriptive, retroprospective study was conducted in patients diagnosed with laryngeal cancer who attended the central consultation for head and neck cancer in the Pinar del Río Province, in the period 2018 - 2021, with the aim of clinically and epidemiologically characterizing this disease in the province. The universe and sample consisted of 128 patients diagnosed with laryngeal cancer who met certain criteria. For information processing, a database was created in SPSS version 11.5 of Windows, with the primary data obtained from the medical records. The results were expressed in number of frequencies and percentages and were represented in tables and graphs for their understanding and presentation. Results: The age group that predominated was 50 to 59 years with 62 patients, (48.4%), with the male sex being the most representative (76.6%) with 98 patients. The skin color that predominated was white (44%). The clinical stage that prevailed most was the relatively late one with 83 patients, (64.8%). The combined treatment was the most used in 60% with 77 patients. The risk factor that was most present in 122 patients was smoking, (95.3%), followed by alcoholism with 97 patients (75.7%). The Municipality that contributed the most cases of this disease was Pinar del Rio with 32 patients, (25%). Consolación del Sur is the second area that contributed the most admissions with 16.4% with 21 patients.
References
1- Molina Ruiz JM, Delportal MJ. Calidad de vida en pacientes tratados con Cancer de Cabeza y Cuello. Acta Otorrinoaringologica Esp [Internet]. 2019 [citado 03 Jul 2022]; 54. Disponible en: http://scholar.google.com.cu/scholar?hl=es&q=Calidad+de+vida+en+pacientes+tratados+con+Cancer+de+Cabeza+y+Cuello.+&btnG=&lr=
2- Amar A, Chedid Helma M, Franzi Altino S, Rapoport A. Retardo diagnóstico e terapêutico em pacientes com câncer da laringe em hospital público de referência. Braz J Otorhinolaryngol. 2019 Dec; 76(6).
3- Cancer Incidence and mortality World Wide: IARC [Internet]. GLOBOCAN [citado 03 Jul 2022]. Disponible en: http//globocan.iarc.fr/
4- Markou K, Christoforidou A, Karasmanis I, Tsiropoulos G, Triaridis S, Constantinidis I, et al. Laryngeal cancer: epidemiological data from Northern Greece and review of the literature. Hippokratia [Internet]. 2021 [citado 03 Jul 2022];17(4):313-8. Disponible en: http://www.ncbi.nlm.nih.gov/ pmc/articles/PMC4097410/pdf/hippokratia-17-313.pdf
5- Organización Panamericana de la Salud HealthSituation in theAmericas. Basic Indicators [Internet]. Washington: OPS; 2021 [citado 03 Julio 2022]. Disponible en: http://ais.paho.org/chi/brochures/2021/BI_2021_ENG.pdf
6- Galera Ruiz H, Ríos Moreno MJ, González Cámpora R, Galera Davidson H. Proteine WNT Net carcinoma squamocellularedella laringe e nel carcinoma del rinofaringe. Acta OtorhinolaryngolItal [Internet]. 2021 [citado 20 Junio 2022]; 32:. Disponible en: http://www.actaitalica.it/issues/2021/3-12/3-2012.htm
7- Jemal A, Siegel R, Xu J, Ward E. Cancer statistics. CA Cáncer J Clin [Internet]. 2020 [citado 24 Junio 2022]. Disponible en: http://onlinelibrary.wiley.com/doi/10.3322/caac.20203/abstract
8- Lence Anta JJ, Fernández Garrote LM. Distribución geográfica del cáncer de laringe en Cuba. Rev Cubana Salud Pública [Internet]. 2019 Sep [citado 19 Julio 2022]; 35(3):. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0864-34662009000300002&lng=es
9- Cuba, Ministerio de Salud Pública. Anuario Estadístico de Cuba 2019 [Internet]. Ciudad de la Habana: MINSAP; 2020 [citado 18 Jun 2022]. Disponible en: http://files.sld.cu/dne/files/2022/04/anuario-2011-e.pdf5
10- Lefebvre JL,Chevalier D. How to Cite or Link Using DOI [Internet]. [citado 12 Julio 2021]. Disponible en: http://www.sciencedirect.com/science/article/pii/S1632347506453066
11- Achiong Estupiñán F, Morales Rigau JM, Dueñas Herrera A, Acebo Figueroa F, Bermúdez González CL, Garrote Rodríguez I. Prevalencia y riesgo atribuible al tabaquismo. Rev Cubana Hig Epidemiol[Internet]. 2020 [citado 11 Junio 2021]; 44(1):. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S156130032006000100001&lng=es&nrm=iso&tlng=es
12- Oblitas G, Colon V, Fuentes MB, García C, Villegas C, Rodríguez JJ. Tratamiento del cáncer de laringe experiencia en el Instituto Oncológico Doctor Luis Razetti. Rev Venez Oncol. 2020 jul-sept; 23(3).
13- Brunetto B. Reflujo Faringolaríngeo: una patología con identidad propia. RevOtorrinolaringolCir Cabeza Cuello. 1998; 58: 129-33.
14- Alert Silva J. La Oncología en Cuba. Ciudad de la Habana, Cuba: Instituto Nacional de Oncología y Radiobiología; 2020.
15- Piyathilake C, Hine R, Dasanayke A, Richards E, FreeberL, Vaughn W, et al. Effect of smoking on folate levels in buccal mucosa cells. Int J Cancer. 1992; 52: 566-9.
16- Lieber C, Garro A, Leo M, Mak K, Worner T. Alcohol and cancer.Hepatology.1996; 6:1005-19.
17- Menvielle G, Luce D, Goldberg P, Bugel I, Leclerc A. Smoking, alcohol drinking and cancer risk for various sites of the larynx and hipopharynx. A case-control study in France. Eur J. Cancer Prev. 2019;13:165-72.
18- Díaz J, López R, Lugo J, Rodríguez C, Cuevas I. Cáncer de la laringe. Experiencia del Instituto Nacional de Oncología. Rev. Inst. Nac. Enf. Mex. 2020;15(4):220-5.
19- Pilarska A. The role of aromatic hydrocarbon hydroxylase in the pathogenesis of lung cancer. Rev Oncol Ed Tyg Lek Pol. 1990;45(14-15):303-7.
20- Koufman J. The otolaryngologic manifestations of gastroesophageal reflux disease, Layngoscope. J. Philadelphia. 2019;101(4):1-78.
21- Vecerina S, Romic R, Krajina Z. Androgen receptors in normal and neoplastic laryngeal tissue. Arch Otolaringol. Head Neck Surg. 2019;113(4):411-21.
22- Castillo-López IY, Govea-Camacho LH, Sánchez-Robles EE, Palacios-López JC. Caracterización clínico-patológica del cáncer de laringe en la población mexicana. Rev Med Inst Mex Seguro Soc. 2021;59(1):27-33. Disponible en internet: http://revistamedica.imss.gob.mx/i
23- Yang PC, Thomas DB, Daling JR, Davis S. Differences in the sex ratio of laryngeal cancer incidence rates by anatomic subsite. J Clin Epidemiol. 1989;42(8): 755-8. http://10.1016/0895-4356(89)90072-3
24- Talamini R, Bosetti C, La Vecchia C, Dal Maso L, Levi F, Bidoli E, et al. Combined effect of tobacco and alcohol on laryngeal cancer risk: a case-control study. Cancer Causes Control. 2021;13(10):957-64. http://10.1023/a:1021944123914
25- Contreras JR, Rich NIklItschek BE, Paredes W A, Cristobal Mass JO. Cáncer laríngeo-hipofaríngeo: Evaluación en el Hospital San Juan de Dios. Rev Otorrinolaringol Cir Cab-Cuello 2020; 61: 19-30.
26- ForastIere aa, GoePFert h, Maor M, PaJak tF, weBer r, MorrIsoN w, GlIssoN B, trottI a, rIdGe Ja, chao c, Peters G, lee dJ, leaF a, eNsleY J, cooPer J. Concurrent chemotherapy and radiotherapy for organ preservation in advanced laryngeal cancer. N Engl J Med 2003; 349(22): 2091-8. http://10.1056/NEJMoa 031317349/22/2091
27- Fajardo GA, Mendoza SH, Valdéz ME, Mejía AM, Yamamoto KL, Mejía DAM, Ayón CA, Bolea MV, Frías VG, Rivera LR, y cols. Frecuencias de neoplasias malignas en niños atendidos en hospitales del Distrito Federal. Estudio multicéntrico. Bol Hosp Infan Mex 2019; 53:57-66
28- Zeitels S, Casiano R, Gardner G, Hogikyan N. Management of common voice problems: Committee report. Otol Head Neck Surg. 2019;126(4):333-48.
29- Managues A. Lesiones precancerosas laríngeas. Ann ORL Mex. 2019;53(4):16774.
30- Mendenhall W, Riggs C. Treatment of head and neck cancers. Rev. Oncol. Ed. Williams. Philadelphia. 2019;12(6):662-732.
31- Flores Díaz R, Martínez Martínez G, Velázquez Chong H. Diagnóstico y tratamiento del carcinoma epidermoide de laringe. CENETEC; 2010. [citado 2022 Oct 27] Disponible en: http://www.cenetec.salud.gob.mx/descargas/gpc/CatalogoMaestro/471_GPC_CaLaringe/ger_cancer_de_ laringe.pdf.
32- Herrera-Gómez A, Villavicencio-Valencia V, Rascón-Ortiz M, Luna-Ortiz K. Demografía del cáncer laríngeo en el Instituto Nacional de Cancerología. Cir Cir. 2019;77(5):353-7.
33- Lim S, Sau P, Cooper L, McPhaden A, Mackenzie K. The incidence of premalignant and malignant disease in Reinke’s edema. Otolaryngol Head Neck Surg. 2019;150(3):434-6. http://10.1177/0194599813520123
34- Dogantemur S, Ozdemir S, Uguz A, Surmelioglu O, Dagkiran M, Tarkan O, et al. Assessment of HPV 16, HPV 18, p16 expression in advanced stage laryngeal cancer patients and prognostic significance. Braz J Otorhinolaryngol. 2020;86(3):351-7. http://10.1016/j.bjorl. 2019.11.005
35- American Cancer Society. Laryngeal and hypopahryngeal cancers overview: Survival rates for laryngeal and hypopharygeal cancers by stage. [citado 2022 Oct 27] Disponible en: http:www.cancer.org/ cancer/laryngealandhypopharyngealcancer/ detailedguide/laryngeal-and-hipopharyngealcancer-survival-rates.
36- Hernández García Ottoniel, Castillo Romero Esther, Rodríguez Gómez Isabel, Albert Rodríguez José Antonio, Fernández Barrera Roberto. Factores de riesgo del cáncer laríngeo. Rev Ciencias Médicas [Internet]. 2014 Dic [citado 2022 Oct 27] ; 18( 6 ): 983-996. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1561-31942014000600006&lng=es.
37- Puñal Riobóo J, Varela Lema L, Barros Dios JM, Juiz Crespo MA, Ruano Raviña A. La ocupación como factor de riesgo del cáncer oral y de faringe. Acta de Otorrinolaringol Esp. 2019; 61(5).
38- Complejo Asistencial Dr. Sótero del Río. Historia. [citado 2022 Oct 27] Disponible en: http://www.hospitalsoterodelrio. cl/home/index.php?option=com_content&view =article&id=45&Itemid=75.
39- Iro h, waldFahrer F, alteNdorF-hoFMaNN a, weIdeNBecher M, sauer r, steINer w. Transoral laser surgery of supraglottic cancer: follow-up of 141 patients. Arch Otolaryngol HeadNeck Surg 1998; 124(11): 1245-50.
40- VIllaseca I, BerNal-sPrekelseN M. Tratamiento de los tumores laríngeos localmente avanzados mediante microcirugía transoral láser. Acta Otorrinolaringol Esp 2021; 64(2): 140149. http://10.1016/j.otorri.2012.01.013
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